Study Details
Testing Povorcitinib for People with Prurigo Nodularis
(IRB#: IRB_00180878)
Prurigo Nodularis is a chronic skin condition known by the presence of hard, extremely itchy bumps known as nodules, which result from persistent, intense scratching and rubbing of the skin. This study will test a drug called Povorcitinib to treat people with this condition. The study wants to see if the drug will help people with the condition and is safe. People in the study will be randomly chosen to be treated with one of two doses of Povorcitinib or a placebo. The placebo looks like the study drug but does not have the medication. Later in the study, people in the placebo group will receive one of two doses of Povorcitinib. Being in the study requires attending up to about 15 in-person visits at the study clinic and two phone or video calls over 13 months. Participants will also write daily in an electronic diary. Medical tests will be done to track the health of participants.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Who can participate?
Gender: All genders
Age: Over 18 years old
Volunteers: Volunteers with special conditions
Location: In Person
Inclusion Criteria
- Ages 18 to 75 years old
- Diagnosis of Prurigo Nodularis
- History of treatment failure to topical corticosteroids
- Able to attend in person at the study clinic
Exclusion Criteria
- Pregnant (or are considering pregnancy) or breastfeeding
- Chronic itching skin due to a condition other than prurigo nodularis.
Will I be paid for my time?
Yes
IRB#: IRB_00180878
PI: zachary Hopkins
Department: SCHOOL OF MEDICINE
Approval Date: 2024-11-20 07:00:00
Specialties: Dermatology
I am Interested