Study Details
Testing Dupilumab in Adults with Eosinophilic Gastritis with or without Eosinophilic Duodenitis
(IRB#: IRB_00171641)
Eosinophilic Gastritis with or without Eosinophilic Duodenitis is a rare disease of the stomach that can cause stomach pain and other health issues. This study will test a drug called Dupilumab to treat adults with this disease. The study wants to see if the drug will help people with the disease and is safe. People in this study will be randomly chosen to be treated with Dupilumab or a placebo. A placebo does not have the medication. The drug and placebo are taken as a liquid injection (a drug given under the skin). The study has 3 parts. Part A of the study people receive the drug or placebo. In part B of the study, people receive different doses of the study drug or the placebo. In part C of the study, all people will receive the study drug. Being in the study may require up to 20 study visits at the clinic for about 1.5 years. Medical tests will be done during the study to track the health of participants. People will be paid for being in the study.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Who can participate?
Gender: All genders
Age: Over 18 years old
Volunteers: Volunteers with special conditions
Location: In Person
Inclusion Criteria
- Ages 18 and older
- Diagnosis of Eosinophilic Gastritis at least 3 months prior to study
- History of at least 2 episodes per week with symptoms such as stomach pain of Eosinophilic Gastritis with or without Eosinophilic Duodenitis
- Attend in person at the study clinic
Exclusion Criteria
- Prior participation in a Dupilumab study participation
- History of other specific diseases or specific prior surgery
- History of bleeding disorders that cause a health risk
- Beginning or change of food diet 4 weeks prior to study participation
- Change in doses of other specific medication 4 weeks prior to study participation
Will I be paid for my time?
Yes
IRB#: IRB_00171641
PI: Kathryn Peterson
Department: INTERNAL MEDICINE
Approval Date: 2024-01-18 07:00:00
Specialties: Gastroenterology
I am Interested